Enterovirus is highly infectious, and it can be infected by contact or droplets, such as contacting the oral and nasal secretion, droplets of sneezing, or eating the food infected with virous from the parents or patients who have asymptomatic infection. Enterovirus can easily spread in family, education institutes and nursery service centers, where toys usually become the media of infection. Enterovirus can be infectious in the few starting days of outbreak. In general, the infective power is the highest within one week after the outbreak of enterovirus.