The epidemic of enterovirus usually occurs in summer and early autumn. Because Taiwan is located in subtropical area, the epidemic of enterovirus is possible to happen in the whole year. According to previous experiences, it reaches the peak time of epidemic in May and June, and it ebbs in July and August due to the summer vacation of students in elementary schools, and then it reaches another peak in September due to the starting of schools. Therefore, people must be careful about it all the time.